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Introduction Personalized medicine is the major goal of tran
2019-04-26
Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease carnosic acid and predict clinical outcome. However, to define a specific disease phenot
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Of additional interest have been rare cases of atypical
2019-04-26
Of additional interest have been rare cases of atypical MLN 9708 fracture reported in women with breast cancer [16,17], described as transverse fractures with focal cortical hypertrophy occurring in the femoral diaphysis with minimal trauma [18]. While atypical fractures were initially reported in
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ion channel Early repolarization ER is characterized by elev
2019-04-26
Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor
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It s finally a year
2019-04-26
It\'s finally 2015: a year by the end of which extreme poverty and hunger are to be eradicated, maternal and child mortality are to be drastically reduced, and the trajectory of the global incidence of HIV, tuberculosis, and malaria are to be reversed. Much has been written about where the Millenniu
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Un tercer gui n si acaso
2019-04-26
Un tercer guión, si acaso el más inquietante de los tres, podría hallarse en la banda de cuatro críticos literarios consagrados comt inhibitor la obra de Archimboldi, el gran autor que Bolaño introduce en la novela 2666. La narración capta una muestra episódica del modo de inserción del intelectual
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Reviewing the literature we knew that
2019-04-26
Reviewing the literature, we knew that in cases of AA, use of IST should be cautious, as IST might accelerate occult lymphoma escaping immune surveillance and evolving as a refractory lymphoma. Second, in cases of AA and concomitant NHL, to choose cytotoxic chemotherapy or IST is an art. Depending o
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Diversos trabajos coinciden en mencionar el impacto positivo
2019-04-25
Diversos trabajos coinciden en mencionar el impacto positivo que la auh ha tenido en términos de inclusión y justicia social frente UNC 0642 la situación donde sólo había asignación familiar contributiva, a partir de variables macroeconómicas como la modificación de tasas de pobreza e indigencia, un
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De esta manera el trabajo se centra en la
2019-04-25
De esta manera, el trabajo se centra en la discusión sobre las fronteras y territorios en el marco de la globalización y transnacionalización, la configuración de nuevos y viejos espacios simbólicos e identitarios, las interacciones y zonas de contacto existentes entre numerosos conjuntos sociocultu
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The measurement of the PPI
2019-04-25
The measurement of the PPI of DP following entrainment pacing usually consists of measuring the interval between the last capturing stimulus and the next DP. This technique is generally based on the assumption that, in the presence of 1:1 capture, pacing depolarizes the zone of slow conduction in th
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br Conflict of interest br Introduction Far
2019-04-25
Conflict of interest Introduction Far-field sensing of the atrial electrogram by a ventricular inhibited (VVI) pacemaker is a rare but potentially catastrophic phenomenon if there is no escape rhythm [1–3]. In this setting, the tip of the pacemaker lead is usually located in close proximity to
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br Conclusion br Conflict of interest br
2019-04-25
Conclusion Conflict of interest Introduction Recent trials of the use of implantable electronic devices, including implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy defibrillators (CRT-Ds) show survival benefits [1–3]. As a result, implantable electronic d
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Cost effectiveness is another major concern for
2019-04-25
Cost effectiveness is another major concern for the governments in countries with public health system. Van-den Hout WB et al. at Netherlands [7] did a cost utility analysis showing the cost of radiation treatment including re-treatment for bone metastases using SF versus MF were €2438 versus €3311
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As with any open label study it
2019-04-25
As with any open-label study, it is possible that a placebo effect may have contributed to patients analgesia after initiation of the therapy. A randomized placebo-controlled trial would be required to finally prove the high analgesic effect of the loading-dose treatment with Ibandronate in metasta
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In addition evidence of similar
2019-04-25
In addition, evidence of similar resting HR׳s before exercise in the patients and in the controls implies similar autonomic activity at rest during the daytime in both groups of subjects. In contrast, previous studies have reported changes in the nocturnal HR of BrS patients [3,28]. The discrepancy
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At the mechanistic level our
2019-04-25
At the mechanistic level, our results strongly suggested that the cholestatic protective effect of STS was most likely accounted for by the activation of LXR, a nuclear receptor known for its anti-cholestatic activity. The activation of LXR was supported by the induction of typical LXR target genes,
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