• Macroautophagy hereafter referred to as autophagy depends on

  2021-12-10

  

  Macroautophagy (hereafter referred to as autophagy) depends on an intracellular lysosome-dependent degradation system that maintains cellular metabolism and homeostasis [11]. Genes involved in these processes are termed autophagy-related genes (ATGs), which regulate autophagosome formation and compl

• Gefitinib hydrochloride Now we turn to the

  2021-12-10

  

  Now we turn to the other channel through which the risk-taking incentives provided by option compensation affect corporate debt maturity. Jensen and Meckling (1976) argue that the payoff structure of debt holders in a levered firm is concave, while that of equity holders is convex, thus, shareholder

• Taken together our studies uncovered that the RP antibody

  2021-12-10

  

  Taken together, our studies uncovered that the RP215 antibody recognize a novel CIgG molecule N-glycan modification at a non-consensus site within the CH1 domain expressed in LSCC tumors. RP215-CIgG interacts with the integrin α6β4 complex and the unique N-glycan epitope mediates the activation of d

• br Introduction Migraine is a chronic neurological disorder

  2021-12-10

  

  Introduction Migraine is a chronic neurological disorder characterized by recurrent episodes of headache. It affects more than 10% of the population worldwide, resulting in a staggering amount of episodic disability, a substantial decrease in the quality of life and a concomitant loss in producti

• Macrophage populations are prominent in active IBD

  2021-12-10

  

  Macrophage populations are prominent in active IBD (Strober and James, 1986) as compared to healthy donors. Further, percentages of macrophages are increased in DSS-induced colitis (Grose et al., 2001, Ogawa et al., 2004). IBD is also linked to an influx of neutrophils and depletion of neutrophils b

• akt inhibitor br Introduction It is well known that conventi

  2021-12-10

  

  Introduction It is well known that conventional cancer treatment strategies, such as surgery, radiotherapy, and chemotherapy all have their own limitations, which lead to an unsatisfactory therapeutic effect. Under this situation, the combination of two or more therapeutic strategies has recently

• Relative to the impact of moderate PAE

  2021-12-10

  

  Relative to the impact of moderate PAE on markers of histaminergic neurotransmission, there were four salient observations from the studies reported here. First, it does not appear that moderate PAE affects the number of HDC-positive neurons in the tuberomammillary nucleus of the ventral hypothalamu

• As an inflammatory mediator histamine plays a pivotal role i

  2021-12-10

  

  As an inflammatory mediator, histamine plays a pivotal role in nociceptive processes in both the central and peripheral nervous systems (Gemkow et al., 2009; Hough & Rice, 2011; Tiligada et al., 2009). In this respect, the participation of H3Rs in modulating pain, especially neuropathic pain, has at

• Cell cell junction proteins were the first upstream

  2021-12-10

  

  Cell-cell junction proteins were the first upstream modules to be characterized as contact sensors through the Hippo pathway. These junctions may be divided in 2 categories: adherens and epithelial polarity junctions. The establishment of intercellular contacts involves the cadherin proteins present

• br Acknowledgments This research was funded by

  2021-12-10

  

  Acknowledgments This research was funded by generous grants from the Singapore National Medical Research Council (NMRC CBRG grant NMRC/CBRG12Nov114 (BD)). WJC is supported by NMRC Clinician Scientist Investigator award and partly supported by a Singapore Cancer Syndicate Grant, the National Resea

• br Cellular directionality To obtain a

  2021-12-09

  

  Cellular directionality To obtain a comprehensive understanding of cell migration, it is essential to understand how cues from the cell’s external environment are relayed to the Bupivacaine HCl receptor cytoskeleton, so the cell can migrate towards the cue; a process herein referred to as cellul

• Regarding the predictive value of the antidepressant

  2021-12-09

  

  Regarding the predictive value of the antidepressant effects of VP2.51 treatment (Fig. 4), different GSK-3 inhibitors produce decreased immobility in forced swim test (Du et al., 2010, Gould and Manji, 2004, Kaidanovich-Beilin et al., 2004, Rosa et al., 2008), with this being a widely used test to a

• Throughout our studies we used CBD under

  2021-12-09

  

  Throughout our studies we used CBD under the assumption that it binds to the GPR55 receptor and has antagonist properties at the GPR55 receptor, as previously suggested (Whyte et al., 2009). To clarify whether the GPR55 receptor is involved in the O-1602-mediated effects on GI motility, we performed

• To further investigate its role in stresses tolerance OsGly

  2021-12-09

  

  To further investigate its role in stresses tolerance, OsGly I was overexpressed in transgenic rice. qRT-PCR and zymologic determination showed that BMS 753 level of OsGly I and the glyoxalase I activity were significantly increased to different extent in the transgenic overexpression lines (Fig. 1

• A majority of aptamer based biosensors

  2021-12-09

  

  A majority of aptamer-based biosensors (termed aptasensors) is based on structure-switching process of aptamer probes upon target binding [[12], [13], [14], [15]]. And canonical structure-switching aptamer probes are strand-displacement aptamer probes, aptamer beacons and split aptamers [[16], [17],

16037 records 553/1070 page Previous Next First page 上5页 551552553554555 下5页 Last page