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npy Despite taking hydroxyurea for months his leukocytosis
2019-06-14
Despite taking hydroxyurea for 6 months, his leukocytosis, splenomegaly, and constitutional symptoms were poorly controlled and his performance status and overall function had declined even further. There was little clinical benefit to gain by increasing the hydroxyurea dose further especially in th
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To assess quality independent from
2019-06-14
To assess quality independent from quantity, Imamura and colleagues assessed dietary intake adjusted for 2000 kcal per day. An unfortunate consequence of this adjustment is that the role of unrestrained energy intake in the obesity and diabetes epidemics seems to be rendered obsolete. For example, i
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Las l neas le comunican a Felipe que l y
2019-06-14
Las líneas le comunican ion channel Felipe que él y sus marañones habían determinado salir De lo primero, denuncia la perversidad de la administración, encabezada por el virrey Cañete, “malo, lujurioso, ambicioso tirano”, quien “premió” a los hombres que combatieron la rebelión de Hernández Girón c
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For many decades scientists have warned that human activity
2019-06-13
For many decades, scientists have warned that human activity is pushing life on our planet beyond the point of no return. In the Earth\'s history there have been five mass extinction events, most recently the Cretaceous–Tertiary mass extinction that occurred almost 65 million years ago and was thoug
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Based on the close relationship of the
2019-06-13
Based on the close relationship of the canine wedge model to human ECGs, individuals with prominent J waves (ERS) or J/ST elevation (BS) are thought to have accentuated ventricular AP notch and the potential to lose their AP dome because of extrinsic factors such as vagal stimulation, sodium channel
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The ventricular integrated HFLP map of each patient from
2019-06-13
The ventricular integrated HFLP map of each patient, from the 187-ch SAVP-ECG, was defined by the increasing gray scale and was superimposed on one spatial distribution map according the site of MI as shown in Fig. 3. The center of the integrated HFLP map of each patient was superimposed on one dist
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Resulta dif cil un censo de poetas aunque la
2019-06-13
Resulta difícil un censo de poetas (aunque la Coordinación Nacional de Literatura del inba o de Conaculta probablemente cuente con las herramientas para hacerlo) y volver gaba receptors trillar sobre un concepto ingenioso como el de asamblea de poetas pergeñado por Zaid en 1980 parece imposible ante
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The district specific estimates of effectiveness figure
2019-06-13
The district-specific estimates of effectiveness (figure 1) include infections averted in all population subgroups over the first 4 years, even for districts without surveys of men who have sex with men and the general population, and the state-level and overall proportion of infections averted acro
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nae inhibitor The region is also suffering from administrati
2019-06-13
The region is also suffering from administrative negligence, extreme poverty, lack of basic health facilities, and weak infrastructure, which have increased its vulnerability to the climatic misery. Travel time to the nearest health facility is 2–4 h, at a cost of PKR 1000–4000 (US$10–40) in a regio
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buy CHIR-99021 br CUANDO EL CUERPO SE HACE ESPACIO El punto
2019-06-13
CUANDO EL CUERPO SE HACE ESPACIO El punto en común de estos lienzos es la ausencia de mirada (figuras 3a y 3b). En el primero los ojos están negros, se presentan las dos órbitas vacías; en el segundo están deliberadamente borrados, ya que incluso se puede distinguir por debajo el contorno de los
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br Discussion To our knowledge we report
2019-06-12
Discussion To our knowledge, we report for the first time t(8;21) acute myeloid leukemia presenting as severe aplastic anemia. t(8;21)(q22;q22) is present in 5–10% of all AMLs, and includes variety of subtypes with varying pathology, and clinical presentations, ranging from circulating blast in p
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br Conclusion br Conflict of interest br Introduction Loss o
2019-06-12
Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu
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Consequently in asymptomatic individuals multiple and repeat
2019-06-12
Consequently, in asymptomatic individuals, multiple and repeated ECG recordings rather than drug testing are recommended for detecting the transient appearance of a spontaneous type 1 ECG, which may indicate the future development of arrhythmic events. Moreover, in addition recording at higher lead
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The fact that interstitial pneumonia was induced at a low
2019-06-12
The fact that interstitial pneumonia was induced at a low dose of bepridil (100mg/day) supports an immunoallergic mechanism rather than a pulmonary toxicity mechanism. In the present case, the dose of bepridil was lower than those in previously reported cases (150–400mg/day) [3] and it was given for
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URMC-099 In bone microenvironment OPG RANK RANKL molecular t
2019-06-12
In bone microenvironment, OPG/RANK/RANKL molecular triad is not solely expressed by bone cells. Whether OPG is considered as a ubiquitary receptor [20], membrane RANK is expressed by various tumour URMC-099 that originate from primary bone tumours or bone metastases, from mesenchymal and epithelial
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